KMID : 1144520200320010059
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Knee Surgery & Related Research 2020 Volume.32 No. 1 p.59 ~ p.59
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Unicompartmental knee arthroplasty and revision total knee arthroplasty have a lower risk of venous thromboembolism disease at 30?days than primary total knee arthroplasty
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Schneider Andrew M.
Schmitt Daniel R. Brown Nicholas M.
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Abstract
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Background: While multiple studies have demonstrated a lower venous thromboembolism disease (VTED) risk for unicompartmental knee arthroplasty (UKA) compared to primary total knee arthroplasty (TKA), recent reports have shown that revision TKA also had a lower VTED risk compared to primary TKA, an unexpected finding because of its theoretical increased risk. Given the paucity of up-to-date comparative studies, our goal was to perform a high-powered VTED risk comparison study of UKA and revision TKA to primary TKA using recent data.
Methods: The National Surgical Quality Improvement Program (NSQIP) database was queried between 2011 and 2018, and we identified 213,234 patients for inclusion: 191,810 primary TKA, 9294 UKA, and 12,130 revision TKA. Demographics, medical comorbidities, and possible VTE risk factors were collected. Thirty-day outcomes, including deep vein thrombosis (DVT), pulmonary embolism (PE), and all-cause VTED were compared between knee arthroplasty types.
Results: On multivariate analysis, UKA was significantly associated with lower rates of DVT [OR 0.44 (0.31?0.61); P?0.001], PE [OR 0.42 (0.28?0.65); P 0.001], and all-cause VTED [OR 0.42 (0.32?0.55); P?0.001] when compared to primary TKA. Revision TKA was significantly associated with lower rates of PE [OR 0.62 (0.47?0.83); P?=?0.002], and all-cause VTED [OR 0.82 (0.70?0.98); P?=?0.029] when compared to primary TKA.
Conclusions: Utilizing recent data from a nationwide patient cohort and controlling for confounding variables, our results showed that both revision TKA and UKA had a lower risk of VTED compared to primary TKA, corroborating the results of recent investigations. Additional prospective investigations are needed to explain this unexpected result.
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KEYWORD
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Total knee arthroplasty, Unicompartmental knee arthroplasty, Venous thromboembolic disease, Revision knee arthroplasty
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